In an October 1992 episode of The Simpsons that spoofs A Streetcar Named Desire, Marge decides to try out for the Springfield Community Center's musical production of "Oh! Streetcar!" Marge plays Blanche, while next-door neighbor Ned Flanders is Stanley and Reverend Lovejoy's wife Helen is Stella. Homer is not in the cast, but he does get into the homage act: when the tab breaks off his pudding can, he stands outside in the yard and screams "Marge!" just as Marlon Brando shouted "Stella!" in A Streetcar Named Desire.

Tweety and Sylvester the Cat starred in a Warner Bros. animated short called A Street Cat Named Sylvester in September 1953, but all connections with A Streetcar Named Desire ended with the title.

There have been two different television movies based on the Tennessee Williams play. In 1984, Treat Williams and Ann-Margret starred as Stanley and Blanche, while Beverly D'Angelo and Randy Quaid filled out the cast as Stella and Mitch, respectively. Then in 1995, Alec Baldwin and Jessica Lange starred in another TV-movie adaptation of Williams' play as Stanley and Blanche. Diane Lane and John Goodman co-starred as Stella and Mitch.

by Scott McGee