"Bad acting and dialogue make this a joy to watch."
- Michael Weldon, The Psychotronic Encyclopedia of Film

"With script and direction proving equally frail, the film is only prevented from becoming the camper's delight promised by the title by the fact that the cast plod through it all with gravity hardly befitting the occasion."
- Tom Milne, MFB [Monthly Film Bulletin]

"Low-budget nonsense, played and directed with little sense of style or purpose."
- Halliwell's Film & Video Guide.

"If Ed Wood hadn't existed, it would not have been necessary to invent him: the world could have lived happily in the knowledge that in William Beaudine we had the next best/worst thing....This was Beaudine's 199th movie and, even though he never reshot a scene, you can sense exhaustion setting in. The fantastic comic/horror/western possibilities of a charismatic outlaw coming into conflict with a girl whose birthright was a bolt through the back of her neck were never really explored. Bizarrely, Beaudine plays this one straight."
- The Rough Guide to Cult Movies.

"...a crude attempt to marry the horror and western genres....it would be unbearable but for [Narda] Onyx, who makes a richly overripe, querulously kinky prima donna out of the mad scientist. Beaudine's last film, it makes a not entirely inappropriate coda to a prolific career down among the Bs."
- Phil Hardy, The Encyclopedia of Horror Movies.

"Outre oater with monster motifs, a blend of cowboys and mad doctor. Result: A laughable disaster that bites the dust. This abomination depicts a pardner of fast-drawing Jesse transmutated into a cactus-chewing Monster dubbed "Igor"....."
- John Stanley, Creature Features.

"...the great, the under-appreciated, the colossally inventive Jesse James Meets Frankenstein's Daughter. The finest horror western ever made - which I realize is like saying the best Mexican wine, but still...Fortunately, this resume-killer of a movie didn't affect the future work of the great Rayford Barnes, as the hothead turncoat outlaw, and Jim Davis, who would become internationally famous as Jock Ewing in "Dallas." William Beaudine, 73 years old when he made this movie, completed more than 500 films in his career, and I can definitely say that this is one of them."
- Joe Bob Briggs

"A companion piece to the simultaneously shot Billy the Kid vs. Dracula, this silly horror-oater needs the bravura of a Carradine to put it over, something this dull cast never does."
- James O'Neill, Terror on Tape

"This, sadly, is an ineptly made gimmick Western...Like its companion piece, Billy the Kid vs. Dracula, this has achieved cult status."
- The Encyclopedia of Western Movies.

"Certainly Jesse James Meets Frankenstein's Daughter has one or two Z-budget howlers - the monster is revived by having a coloured motorcycle helmet placed on his head, or the moment when Maria invites Jesse to come into her library and the resulting room contains no books. It should also be noted that despite the title Narda Onyx plays Frankenstein's granddaughter, not his daughter. But for all its Z-movie reputation, Jesse James is never really any worse than a B western. It doesn't look all that cheap and is in colour. There are certainly a lot of genre films worse than this. Narda Onyx gives a wonderfully breathy and overwrought performance as Maria and John Lupton is quite good as Jesse, as is Estelita as the good-hearted Juanita."
- Richard Scheib, The SF, Horror and Fantasy Film Review.

"That bare outline of the plot doesn't begin to get at just how aimless and silly the movie really is. There are moments of utter nonsense, yet too much of the movie involves long, seemingly endless sequences of characters talking and talking and talking, as if plot points are really crucial...The western elements are never very exciting, and the horror elements are certainly never scary, although they do have a genuinely enjoyable kitsch value, particularly when Maria Frankenstein starts espousing her fervent dreams and desires of creation. Narda Onyx turns Maria into a memorably campy screen villainess, one that deserves a much better movie than this one."
- James Kendrick, www.qnetwork.com

"Are there worse films than Jesse James Meets Frankenstein's Daughter? Of course there are, but you have to really dive deep to find them. This piece of entertainment goes horribly bad even before you reach the end of reading the title, as the character in the film is not even Dr. Frankenstein's daughter but his grand-daughter. And as you begin viewing, you'll notice her brother Rudolph is played by an actor 30 years her elder. And just seconds later you see that a key piece of her lab equipment in transplanting brains is a World War II army helmet painted in rainbow stripes – and well, there but for the grace of God, go your great expectations."
- Alameda TV, www.alamedatv.org

Compiled by Jeff Stafford