- Walter Matthau says "gesundheit" three times during the movie.
- The Transit Authority (TA) of New York at first refused to allow the film to be shot on the actual New York subway. They feared it would lead to imitative crime (it didn't, but their position was shown to be reasonable when the later film Money Train (1995) apparently did). Associate producer Stephen F. Kesten was equally adamant that no other city's subway could be credibly used (and he was apparently right: see the goofs entry for the remake Taking of Pelham One Two Three, The (1998) (TV)). The TA finally did cooperate after Mayor John V. Lindsay intervened, but they required United Artists to buy anti-hijacking insurance at a cost of $75,000 in addition to paying $275,000 for the use of the subway.
- Walter Matthau had not been on the New York subway in many years at the time this movie was made even though he was born and raised in New York.
- Filmed mostly in the tunnels leading to the decommissioned IND Court St. station in Brooklyn. The station itself served as Grand Central and 28th St.
- Ever since the release of the film, no number 6 train has ever been scheduled to leave Pelham Bay Park at either 13:23 or 01:23.
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