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The film opens with the following prologue: "New Orleans-Crescent City of the Old South-where Rex, the King of Mischief, Reigns Over the Mardi Gras For One Mad Week." According to news items in Hollywood Reporter, producer Herbert Wilcox bought the rights to the play from Warner Bros. as a vehicle for Anna Neagle. This was the third musical comedy collaboration between RKO, Neagle and Wilcox. In 1940, Wilcox and Neagle adapted the musical comedies Irene and No, No Nanette to the screen (see AFI Catalog of Feature Films, 1931-40; F3.2156 & F3.3161). According to another news item in Hollywood Reporter, Ken Englund was hired to write the screenplay, but his contribution to the final film has not been confirmed.
Other news items in Hollywood Reporter yield the following information: May Robson was prevented from playing the role of "Aunt Barbara" because of a prior commitment. J. Roy Hunt shot the Mardi Gras backgrounds in New Orleans. Vaudeville performer Muggins Davies ended fifteen years of retirement to play "Muggins" in this film. John Carroll was loaned from M-G-M to appear as "Larry Warren." A news item in New York Times adds that Ernestine Clark, who doubled for Anna Neagle in the film, was a famed equestrienne and aerialist for the Ringling Bros. circus. This picture was nominated for an Academy Award for Best Score. A previous adaptation of the Otto Harbach, Oscar Hammerstein II and Jerome Kern play was filmed by Warner Bros. in 1930, directed by William Seiter and starring Marilyn Miller, who played the role on Broadway (see AFI Catalog of Feature Films, 1921-30; F2.5465). According to news item in Los Angeles Times, in 1952 Warner Bros. was planning to film an updated version of the play starring Doris Day, but that film was never made.