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According to documents in the Twentieth Century-Fox Records of the Legal Department at the UCLA Arts-Special Collections Library, in July 1947, Gwen Davenport's novel was adapted from her unpublished, three-act play Squatter's Rights. Early in September 1947, a pre-production news item announced that John Payne and Celeste Holm would appear in Sitting Pretty along with Maureen O'Hara and Clifton Webb. Although the CBCS lists Dorothy Adams as appearing in the film, her character was eliminated before the film's release.
Two sequels featuring the "Mr. Belvedere" character were produced by Twentieth Century-Fox: Mr. Belvedere Goes to College and the 1951 film Mr. Belvedere Rings the Bell. Both films starred Clifton Webb, who received an Academy Award nomination as Best Actor for Sitting Pretty. In addition, Fox planned three additional "Mr. Belvedere" films for which scripts were written, but not produced. A radio version of Sitting Pretty, featuring Webb and Robert Young, was broadcast on the Lux Radio Theatre on February 14, 1949. In 1956, F. Hugh Herbert's script was remade as Mr. Belvedere for the CBS television series The 20th Century-Fox Hour. That version starred Reginald Gardiner, Eddie Bracken and Margaret Hayes. Pilots for a Belvedere television series were shot in 1959 with Hans Conried and, in 1965, with Victor Buono, but were never sold. From 1985 to 1990, the ABC network broadcast Mr. Belvedere, a television sitcom featuring Christopher Hewett in the title role.