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The working titles for the film were Sexpot Goes to College, Teacher Versus Sexpot and Teacher Was a Sexpot. The CBCS refers to the actress known as Vampira by her real name, Maila Nurmi. According to a December 2, 1959 Hollywood Reporter news item, Aram Katcher, who was to play the role of "Dr. Ernest Zorch," quit the production and was replaced by Louis Nye.
Sex Kittens Go to College was the American film debut for Mijanou Bardot, sister of French film star Brigitte Bardot. Although the film included several songs by Conway Twitty, none of the titles have been verified. Albert Zugsmith also directed, produced and wrote a similar college romp in 1960 entitled College Confidential, which shared some of the same cast, including Mamie Van Doren, Mickey Shaughnessy, Woo Woo Grabowski, Pamela Mason, Arline Hunter and singer Conway Twitty (see entry above).