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A copyright notice is listed on the film for Madera Productions, but The Screaming Skull was not registered for copyright at the time of its release. However, a Mystery Science Theatre 3000 video version of the film was registered on September 8, 1998. John Kneubuhl's onscreen credit reads: "Produced and Written by John Kneubuhl." Toni Johnson's name was misspelled in the opening credits as "Tony Johnson." Makeup artist Don Robertson's name was misspelled as "Roberson" in the credits.
Prior to the opening credits, the following spoken prologue is heard as a casket slowly opens: "The Screaming Skull is a motion picture that reaches its climax in shocking horror. Its impact is so terrifying it May have an unforeseen effect: it May kill you. Therefore, its producers feel they must assure free burial service to anyone who dies of fright while seeing The Screaming Skull." The scene concludes with a closeup of the inside of the casket in which a card reads: "Reserved for You."