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The film opens with a voice-over narration delivered by Charles Drake as "Pvt. Partridge," outlining the 1944 Allied invasion to free Europe. The title credit does not appear until Partridge's narration is completed, about fifteen minutes into the film. The onscreen production and cast credits are withheld until the end of the film. The picture closes with the following written acknowledgment: "We gratefully acknowledge the cooperation of the Department of Defense, the Transportation Corps of the Army and the Virginia National Guard in the making of this motion picture."
As depicted in the film, the Red Ball Express, formally known as the 371st Quartermaster Truck Company of the Army Transportation Corps, was a division of 6,000 trucks formed by Major General Frank Ross, the film's technical adviser, to rush ammunition, gasoline and other supplies through enemy held territory to General George Patton's tanks. The division included many African American soldiers. According to the Hollywood Reporter review, location scenes for this picture were shot at Fort Eustis, VA, the headquarters of the Army Transportation Corps. Although a Hollywood Reporter production chart places Susan Cabot and Richard Garland in the cast, their participation in the released film has not been confirmed.