- The cavalry sequences were shot with members of the Wyoming National Guard. Two guardsmen were badly hurt during filming of a charge scene.
- 2,000 Indian actors were used as extras for the Custer massacre sequence.
- Paramount executives wanted Wild Bill Hickok to survive the card-game shootout, but director DeMille resisted and got his way.
- Anthony Quinn told Cecil B. DeMille that he spoke fluent Cheyenne. Quinn's description of the Custer Battle is gibberish, but DeMille was impressed.
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