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The working titles of this film were Oh, Say, Can You Swing?, You Can't Ration Love and School for Jive. According to Hollywood Reporter, the film's release title was changed from School for Jive to Mister Big in order to promote rising Universal star Donald O'Connor. Universal press materials further state that Mister Big was designed to be the first "star vehicle" for O'Connor. A February 5, 1943 Hollywood Reporter news item announced a planned Universal project entitled Benny Goes to Town, starring O'Connor, Gloria Jean, Peggy Ryan and Bobby Scheerer, and directed by Charles Lamont. It has not been determined if this project became Mister Big or was another project that was replaced on the Universal production schedule by Mister Big. Mister Big marked the feature film debut of child actress Mary Eleanor Donahue.