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John Cassevetes' onscreen credit reads: "Written and directed by." Portions of the film were shot on location in Los Angeles and New York, according to Hollywood Reporter production charts. Pink's Hot Dogs, the first restaurant to which "Moskowitz" takes "Minnie," is a well-known family-owned establishment, which has been in existence in Los Angeles since 1939. Gena Rowlands, who portrayed Minnie, was Cassavetes' wife and frequent star, and cast members Katherine Cassavetes, Lady Rowlands and David Rowlands were members of his family. According to Filmfacts, three Cassevetes children appear in the final sequence. Elizabeth Deering, who portrayed the woman with whom Moskowitz has a one night stand, and Elsie Ames, who portrayed "Florence," were the wife and mother-in-law, respectively, of Seymour Cassel, who portrayed Moskowitz. Modern sources add Bruce Brown and Darlene Conley to the cast.
Gena Rowlands was nominated Best Actress by the New York Film Critics. Minnie and Moskowitz was listed in the year's top ten best films by Cue, Newsday and Time magazines. A novelization of the film was published in 1973 by Black Sparrow Press.