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Harry Mitchell has absconded with $500,000 of Mafia leader Riccione's money, and Dano Villanova is assigned to kill him before he reveals any organization secrets to the police. At the same time, Sol Madrid, an undercover narcotics agent, begins a search for Mitchell, hoping to persuade him to testify against the Mafia. Madrid finds Villanova's former mistress, Stacey Woodward, who has half the stolen money, and learns from her that Mitchell is in Acapulco. Threatening to inform Villanova of her whereabouts, Madrid forces Stacey to accompany him to Mexico and there she introduces him to both Mitchell and Emil Dietrich, a leading supplier of heroin who has also recently broken with the Mafia. Posing as a border runner, Madrid works his way into Dietrich's confidence despite Mitchell's skeptical objections. With the assistance of Mexican agent Jalisco, Madrid spirits Stacey away in a yacht while he baits the final trap for the narcotics smugglers. But, before he can execute his final plan, she is kidnaped by Villanova and forcibly turned into a dope addict. Then, after Mitchell has been murdered, Madrid enlists local police assistance and learns that Jalisco is a Mafia payoff man. After shooting Dietrich, Madrid corners Jalisco, forces him to reveal Villanova's hiding place, and then kills him. Finally, Madrid tracks down Villanova in a dense jungle and disposes of him also; and in a hospital bed Stacey slowly recovers from her addiction.