Growing up together, Mitch and Dave were inseparable best friends, but as the years have passed they've slowly drifted apart. While Dave is an overworked lawyer, husband and father of three, Mitch has remained a single, quasi-employed man-child who has never met a responsibility he liked. To Mitch, Dave has it all: beautiful wife Jamie, kids who adore him and a high-paying job at a prestigious law firm. To Dave, living Mitch's stress free life without obligation or consequence would be a dream come true. Following a drunken night out together, Mitch and Dave's worlds are turned upside down when they wake up in each other's bodies and proceed to freak out. Despite the freedom from their normal routines and habits, the guys soon discover that each other's lives are nowhere near as rosy as they once seemed. Further complicating matters are Dave's sexy legal associate, Sabrina, and Mitch's estranged father. With time not on their side, Mitch and Dave struggle to avoid completely destroying each other's lives before they can find a way to get their old ones back.

Mitch and Dave were best friends who grew apart. Stable husband and father of three, Dave has little in common with irresponsible, single Mitch. Both envy each other's lives until they wake up in each other's bodies.