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Actors Vera Zorina, Irene Bordoni, Victor Moore, Charles Laskey and Lynda Grey appeared in the original stage production of the play, which had been produced by Paramount production head B. G. DeSylva. According to a New York Times news item, Paramount purchased the rights to the hit play for $150,000. Variety notes that except for a new finish, the film was "an almost literal translation from the stage." Hollywood Reporter news items indicate the following: Ethel Merman was initially considered for a leading role in the film; New York fashion model Laurie Douglas was cast, but her appearance in the final film has not been confirmed; the airport scene was filmed on location at Lockheed Aircraft in Los Angeles, CA. This film marked the motion picture debut of actress Jean Wallace. Louisiana Purchase was nominated for Academy Awards in the following categories: Cinematography (Color), Harry Hallenberger and Ray Rennahan; and Art Direction/Interior Decoration (Color), Raoul Pne du Bois/Stephen Seymour.