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In Victorian London, Dr. Henry Jekyll experiments with drugs in an attempt to separate the good and evil natures of man. One night he injects himself with his personality-changing serum, and the somber Jekyll is transformed into the debonair Mr. Hyde. He visits the Sphinx, a West End nightclub, where he encounters Jekyll's neglected wife, Kitty, dancing with his close friend, Paul Allen, an inveterate gambler. Though Jekyll tries to submerge the evil nature of Hyde, he cannot prevent himself from plotting Paul's death, and he lures his former friend into the dressing room of Maria, a snake dancer. As the terrified Paul is crushed to death by a python, the bestial Hyde assaults Kitty. Following the rape, the hysterical woman throws herself off the balcony to her death. By now the character of Hyde has taken almost complete possession of Jekyll. After murdering Maria during a moment of passion, he kills a stableboy, places his body in Jekyll's laboratory, and sets it aflame. Hyde identifies the charred body as Jekyll and convinces the police that the doctor was the deranged killer responsible for the recent deaths. At the coroner's inquest, however, the character of Jekyll emerges, and the true facts of the case are finally revealed.