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The working titles of this film were Miss Baker's Dozen and Snips and Snails. "Her Twelve Men" was also the title of an excerpt of Louise Baker's novel Snips and Snails that appeared in Ladies Home Journal in December 1953. The film opens with a montage sequence, narrated by Greer Garson as "Jan Stewart," depicting Jan's childhood fantasies about a glamorous future. The character continues to provide voice-over narration throughout the first part of the film. June 1952 Hollywood Reporter news items report that Sidney Franklin was originally assigned to produce the film. In his memoir, John Houseman recalled that Garson requested him as producer, and he reluctantly agreed. "I spent little time on Miss Baker," Houseman wrote. "My only positive contribution was the addition to the cast of my friend Robert Ryan, who was trying to shed the stigma of playing only brutal and violent parts." Houseman added that he seldom visited the set during production: "After a few tedious arguments with [Robert Z.] Pop Leonard, I stopped checking on the directorial methods of this ancient, experienced man who had directed Miss Garson in Pride and Prejudice more than a dozen years before."
Timothy Marker, who appeared in the film as "Tommy," was the grandson of silent film star Francis X. Bushman. Her Twelve Men was the last film Garson made under her contract with M-G-M. Garson was signed by the studio when she made her motion picture debut in the 1939 film Goodbye, Mr. Chips (see AFI Catalog of Feature Films, 1931-40). She returned to the studio, along with a number of other former M-G-M contract stars, for the 1965 film The Singing Nun.