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The working title of this film was Volcano. According to a July 1953 Daily Variety news item, the working title was changed because "there is an Italian pic of same title now playing U.S. art houses," which referred to the 1953 film Volcano, directed by William Dieterle and starring Rosanno Brazzi and Anna Magnani. According to a September 1953 Hollywood Reporter news item, Robert L. Jacks was orginally set to produce Garden of Evil, but left Twentieth Century-Fox to join Panoramic Productions and was replaced by Charles Brackett. According to studio publicity, outdoor sequences for the film were shot on location in Mexico, at "the colonial town" of Tepatzlan; the jungle areas alongside the Los Concheros River near Acapulco, Parcutin Mountain, which was surrounded by black volcanic sands; and the village of Guanajuato. Hollywood Reporter news items add that interior scenes were shot at the Churubusco Studios in Mexico City.