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According to Hollywood Reporter news items, "background and atmospheric shots" for this picture, which was to have a budget of $500,000, were filmed in Mexico City. Some scenes were also shot in Lone Pine, CA. Hollywood Reporter also noted that George Carleton Brown was signed by Republic to write a treatment, but his contribution to the completed picture has not been confirmed. Republic contract player Mary Lee was scheduled to appear in the film, but she was removed from the cast when the studio decided to feature her more prominently in "solo pictures." Although the Variety review stated that Fay McKenzie was making "her first screen assignment" in Down Mexico Way, she had appeared in numerous films in the 1930s. Modern sources include the following actors in the cast: Reed Howes, Hank Bell, Fred Burns, Al Haskell, Jack O'Shea and Frankie Marvin.