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Onscreen credits indicate that footage from the following Mack Sennett shorts, among others, was used in the film: Sing, Bing, Sing (1933), starring Bing Crosby and directed by Babe Stafford; Blue of the Night (1933), starring Bing Crosby and directed by Leslie Pearce; The Singing Boxer (1933), starring Donald Novis and directed by Leslie Pearce; and The Dentist (1932), starring W. C. Fields and directed by Leslie Pearce. A September 27, 1949 Hollywood Reporter news item notes that all surviving members of the Keystone Cops-Andy Clyde, Chester Conklin, James Finlayson, Hank Mann, Vernon Dent, and one of their directors, Del Lord-rode a paddy wagon to the film's opening. Down Memory Lane marked Steve Allen's motion picture debut.
Modern sources identify the following actors from still photographs of the film: Andre Bailey, Anita Barnes, Lois Boyd, Betty Bird, Margaret Cloud, Julie Duncan, Ceille Evans, Dot Farley, Eugenia Gilbert, Eddie Gribbon, Ruth Hiatt, Thelma Hill, Madeline Hurlock, Bud Jamison, Mildred June, Natalie Kingston, Carole Lombard, Delores Mendex, Reggie Morris, Thelma Parr, Kalla Pasha, Della Peterson, Elsie Tarron, Gladys Tennyson, Eva Thatcher, Mary Thurman, Bobby Vernon and Toby Wing.