- In the film, Ronald Colman plays a fictional actor who stars in the longest-running "Othello" in history. In real life, actor Paul Robeson, who had just become the first black actor to star in an otherwise white production of "Othello" on Broadway, had just completed the longest run of the play.
- The role of Anthony John was originally written for Laurence Olivier. Olivier was unavailable when the film finally went into production.
- The "Othello" scenes were filmed separately and in the exact order in which they occur in Shakespeare's play, so as to give Ronald Colman the feeling that he was actually appearing in "Othello". Colman felt uneasy about performing Shakespeare, so director George Cukor and Shakespearean actor Walter Hampden, who acted as coach and advisor for these scenes, tried to make Colman as comfortable as possible in them.
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