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The working titles of this film were Dangerous Living, Pier 23 and Roaring City. Voice-over narration spoken by Hugh Beaumont as "Dennis O'Brien" is heard intermittently throughout the picture. The opening credits contain the following description of the film: "An adventure presented in two parts-each a complete story." Danger Zone comprised two unrelated stories involving the characters portrayed by Hugh Beaumont, Edward Brophy and Richard Travis.
Danger Zone was based on the short-lived 1947 radio series Johnny Modero: Pier 23, in which Jack Webb portrayed a detective working out of the San Francisco waterfront. "Johnny Modero" was modeled on "Pat Novak," a character Webb had played the previous year on Pat Novak for Hire, a program produced by San Francisco radio station KGO. Like Novak, Modero had a hard-drinking assistant and a nemesis in the police department. Pat Novak for Hire was subsequently recreated for the ABC radio network (1949-1950).
According to the Hollywood Reporter review, the film was "one of [Lippert's] experimental productions designed for release in two installments to television after making the theatre rounds. Lippert produced two additional "Dennis O'Brien" films, Pier 23 and Roaring City (see below), also featuring the same central characters in two separate murder mysteries and both released in 1951. A January 12, 1951 Hollywood Reporter news item adds Rebel Randall, Greg McClure and William Tannen to the cast; however, their appearance in the released film has not been confirmed. Portions of the film were shot on location in San Francisco, CA.