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The tomb of Ra-Antef, the pharaoh, is excavated in 1900, and soon afterwards archeologist Professor Dubois is murdered. American showman Alexander King, who is financing the expedition, wants to take the remains and artifacts on an exhibition tour, despite the warnings of archeologists and Hashmi Bey, the Egyptian advisor, that violating the tomb activates its curse. En route to London, the party experiences the effects of the curse. John Bray, the boyfriend of Professor Dubois' daughter Annette, is attacked but is saved by Adam Beauchamp, who falls in love with Annette. As the exhibition is about to open, the mummy case is found to be empty. Ra-Antef fulfills the curse by murdering King, expedition leader Sir Giles Dalrymple, and Hashmi Bey and by abducting Annette. Beauchamp, really Ra-Antef's brother, is revealed to be cursed with immortality because he killed Ra-Antef. He confronts his brother in the sewers, asking Ra-Antef to kill him and also Annette so that they may spend eternity together. John Bray and Inspector MacKenzie are able to rescue Annette as Ra-Antef destroys both himself and his brother.