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Nancy lives in mortal fear of her foster father and, when he attacks her, she kills him in a moment of panic. The murder is discovered by Jim, a young hobo, who helps her to escape. Nancy dresses in men's rough clothes, and she and Jim hop a freight; thrown off by the brakeman, they take refuge in a hobo camp, the leadership of which is bitterly contested between Arkansas Snake and Oklahoma Red. The encampment is broken up by detectives, and Jim and Nancy take refuge with Mose and a seriously ill tramp in an abandoned shack. Red unexpectedly shows up with a stolen car and women's clothing for Nancy, helping her and Jim to escape in the car. The sick tramp dies, and Red, dressing him in Nancy's rough clothes, places his body in a lumber car which he sets aflame. The pursuing detective kills Red, and Jim and Nancy (who is declared to be officially dead by the police) hop a passenger train for Canada.