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The working titles of this film were Duet and Actor's Blood. The picture consists of two sections, entitled Actor's Blood and Woman of Sin, each based on a screen story written by Ben Hecht. Although the reviews refer to the film as Actors Blood, the onscreen title card reads: Ben Hecht's ACTOR'S blood AND woman of SIN. Hecht's onscreen credit reads: "Written, Produced and Directed by Ben Hecht." Lee Garmes' onscreen credit reads: "Co-Director Lee Garmes, and Director of Photography." The opening cast credits list Edward G. Robinson, Eddie Albert and Marsha Hunt above the title, with full cast lists preceding each section of the film as shown above.
The Actor's Blood section begins with a voice-over narration by Dan O'Herlihy as "Alfred O'Shea," describing "a tale that could happen only in the city of New York, and only amongst people of the theater." The Woman of Sin section starts with a voice-over narration by Hecht that describes the "mad" days of Hollywood's past in which the irresponsible, shyster agents reigned supreme. Hecht's daughter Jenny starred as "Daisy Marchand." Specific Los Angeles locations, such as Grauman's Chinese Theatre and the Brown Derby, are shown, and real-life Hollywood moguls such as David O. Selznick are mentioned.
According to a July 1952 Los Angeles Mirror article, the Beverly Canon theater in Beverly Hills booked Actor's and Sin after the film received rave reviews in New York. After viewing the print, however, the exhibitors feared that Los Angeles audiences would be offended by the picture's ridiculing of Hollywood, and cancelled the engagement. Hecht then filed a suit requesting $250,000 in damages or an injunction to compel the Canon to show his film. The Los Angeles Mirror article further states that United Artists and Sid Kuller filed a similar suit. Later in Jul, Variety reported that Hecht conducted a radio interview in which he blasted the Canon and Hollywood for their inability to make fun of themselves. Even though the Canon then opted to run the film in late Jul, an August Variety item stated that Kuller was angry with Hecht for "scaring away business." Although the Hollywood Reporter review lists the running time as 94 minutes, this time was probably a misprint. Although a Hollywood Reporter news item stated that Kit Guard was to have a key role in the film, Guard's appearance in the released film has not been confirmed.