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When Grace drops out of sight in a metropolis, her brother, Eddie, a simple country boy, goes to the city to look for her. He finds work in a department store and meets Fanny O'Rell, a city girl who introduces him to narcotics; Eddie soon becomes an addict and loses his job. Turning into a tormented derelict, Eddie wanders the city streets and meets up with Grace, who, an addict also, has become a prostitute. Grace is jailed, and Eddie enters a hospital, where, after months of agony, he is cured of his habit and allowed to return home to the welcoming arms of his family and his childhood sweetheart.