In Winnebago, Wisconsin, a Jewish family comprising Molly and Ferdinand Brandeis and their two children, Fanny and Theodore, run a modest dry goods store. Theodore is studying violin and auditions for a famous violinist, The Great Schabelitz, who is giving a local concert. Schabelitz is impressed by the boy's talent and recommends that he plan to study in Dresden, Germany. After Ferdinand dies, the family makes many sacrifices to enable Theodore to study in Dresden, where he eventually marries a worthless chorus girl and causes his mother's death from a broken heart. Although she continues to contribute to Theodore's support, Fanny decides to live her own life and moves to Chicago. There she becomes a highly efficient businesswoman in a department store, spurred on by her colleague and admirer Michael Fenger, who is trapped in a loveless marriage. A former school friend, Clarence Hyle, also attempts to woo Fanny. Later, Theodore, who has been deserted by his wife, returns from Europe with his baby daughter and comes to live with Fanny. When he eventually becomes a successful performer, he leaves Fanny a message saying that he is returning to his wife. After so much self-sacrifice, Fanny decides to live only for herself and is about to sail to Honolulu with Fenger when Clarence makes her realize that her true happiness lies with him.