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The working title of the film was Alma Mater. According to a modern source, Douglas Morrow and Robert Hardy Andrews' original story was entitled "It Figures." November 1952 Hollywood Reporter news items add actors Paul Brady, Margaret Barstow, Sam Innes and Parry O'Brien to the cast, but their appearance in the film has not been confirmed. According to Warner Bros. production notes, portions of the film were shot at Pomona College, various Los Angeles high schools, including Loyola, and Cathedral Chapel in La Brea, CA.
A June 1953 Hollywood Reporter news item reported that actress Sherry Jackson had been named "Best Child Performer for 1952-53" by the General Federation of Women's Clubs for her work in Trouble Along the Way, The Miracle of Our Lady of Fatima and The Lion and the Horse ( entries). Jackson and actor Tom Tully reprised their roles in a February 15, 1954 Lux Radio Theatre adaptation, starring Jack Carson, June Haver and Herbert Butterfield. Jackson appeared again in a March 29, 1955 revised Lux adaptation of Trouble Along the Way, this time co-starring with Van Johnson, Joanne Dru and Parley Baer.