It is 1933, and eight years have passed since dashing legionnaire Rick O'Connell and fearless Egyptologist Evelyn fought for their lives against a 3000-year-old enemy named Imhotep. Rick and Evelyn are married now, raising their son Alex in London. A chain of events finds the mummy of Imhotep resurrected in the British Museum, walking the earth once more in his search for immortality. But another force has also been set loose in the world - one born of the darkest rituals of ancient Egyptian mysticism, and even more powerful than Imhotep. When these two forces clash, the fate of the world will hang in the balance, sending the O'Connells on a desperate race to save the world from unspeakable evil and rescue their son before it's too late.

The remains of a mummy are brought to a London museum and revived.