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A May 1942 Hollywood Reporter news item indicates that M-G-M purchased the film rights to Philip Barry's play for $265,000. The original New York run of the play starred Elliott Nugent and Katharine Hepburn, who reprised her stage role for this film. Hollywood Reporter news items in September 1943 indicate that production on the film, which was originally set to begin before November 1943, was postponed due to the unavailability of Hepburn and director Harold S. Bucquet, who were both involved in the production of the film Dragon Seed. Hollywood Reporter production charts list actor Robert L. Hartzell in the cast, but his appearance in the released film has not been confirmed. Without Love was one of the top grossing films of 1945. Rommy, the cairn terrier in the film, also appeared with Hepburn in the 1946 M-G-M film Undercurrent. Without Love was the final picture of director Harold S. Bucquet, who died of cancer in 1946. Bucquet began his film career directing shorts, and directed his first feature film, for M-G-M, in 1938.