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The working title of this film was The Doctor's Husband. According to pre-production news items in Hollywood Reporter, director Wesley Ruggles unsuccesfully sought Norma Shearer, Helen Hayes, Katharine Cornell and Valerie Hobson to star in this picture. Madeleine Carroll, June Havoc, Virginia Greenwood, Claire Niesen and Australian comedianne Zaide Laselmo were also considered for roles in the film. According to a August 13, 1941 Hollywood Reporter news item, additional scenes of Fritz Feld as the comic hotel clerk were shot after the completion of principal photography. You Belong to Me was Ruggles' last production for Columbia. On June 15, 1942, the Lux Radio Theatre broadcast a version of this story starring Merle Oberon. In 1950, Columbia produced another version of the film, titled Emergency Wedding.