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An August 1951 Hollywood Reporter news item reported that Gene Nelson had initially been cast in the film. About Face marked the film debuts of Joel Grey, a protg of Eddie Cantor, Mabel Albertson and Aileen Stanley, Jr., according to August and September 1953 Hollywood Reporter news items and Warner Bros. production notes. The production notes also add to the cast Patricia Hawks, daughter of former actress Bessie Love. Although her appearance has not been confirmed, September 1953 Hollywood Reporter news items add Doris Fulton to the cast. An August 1951 Hollywood Reporter news item stated that director Roy Del Ruth played a professor in the film. College exteriors were shot at the campus of the University of California at Los Angeles.
An August 1952 Variety news item reported that Warner Bros. was being sued over their use of the title About Face, as it conflicted with the 1942 United Artists picture, titled About Face, which was produced by Hal Roach. The plaintiffs were Favorite Films Corp. and Favorite Films International Corp., who owned reissue rights to the 1942 film, and Regal Television Corp., who picked up the television rights. The outcome of the lawsuit has not been ascertained. Warner Bros. made an earlier adaptation of John Monks, Jr. and Fred F. Finklehoff's play, the 1938 film Brother Rat, which was directed by William Keighley. For more information about the 1938 film, its sequel, and the play Brother Rat, see the entry in AFI Catalog of Feature Films, 1931-40.