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Harry, a British Grenadier Guard, decides to investigate when he learns that his brother has mysteriously died in a Cornish village. Although the townspeople are secretive and hostile to Harry and his wife, Valerie, the two learn that the brother died from a snakebite on his neck. Subsequent investigation reveals that Anna, the daughter of Dr. Franklyn, the local physician, had been cursed by Malayan natives when she and her father lived in Borneo. As a result, Anna turns into a snake when exposed to intense heat. After Harry is lured to the house and bitten by the snake creature, Valerie also visits the house and a struggle ensues during which an overturned lamp sets fire to Dr. Franklyn's home. The blaze transforms Anna into a huge reptile, and she buries her fangs in her father before perishing in the flames. Harry manages to save Valerie, and the two escape from the burning house.