- When Nick is resting in the hammock in his parent's front yard, he is reading a "Nick Carter, Detective" comic book.
- Liberal drinking of alcohol, a mainstay of the first four "Thin Man" movies, was curtailed for this movie due to wartime liquor rationing.
- Norman Taurog directed the additional scenes filmed in August and September, 1944, because Richard Thorpe had begun work on his next film Thrill of a Romance (1945).
- The Charles' dog, Asta, was replaced for this movie. The original dog outgrew the part.
- This movie was to begin production in 1942, but Myrna Loy refused the part. Instead, she went to New York to marry car rental heir John Hertz, Jr., and worked for the Red Cross war-relief effort. The movie almost began shooting with Irene Dunne as Nora Charles.
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