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The working titles of this film were Then There Were Two and Along Came...Murder. Although a December 1941 Hollywood Reporter news item lists Diane Dorsey in the cast, her appearance in the released film has not been confirmed. According to a December 1941 Hollywood Reporter news item, Lee Jones, who worked as technical advisor on the crime detection scenes in this film, was a member of the Los Angeles police departments chemical division. The Austrian-born Fred Zinnemann had worked in the U.S. as a director of documentaries and short subjects for many years. Although he had some co-directing feature credits prior to Kid Glove Killer, this was the first film on which he received sole directing credit. The film garnered favorable reviews with the New York Times noting that it was "a little crackerjack of a picture." Modern sources add Robert Blake to the cast as the boy in the cab.