- The first choices for the lead roles were John Mills and Bette Davis.
- The scenes in the reed-filled riverbank were filmed in Dalyan, Turkey.
- Originally offered to Bette Davis in 1938, the film would have co-starred David Nivenas Charlie. It was offered to Davis again in 1947, this time to co-star James Mason, but she had to pull out of the project due to pregnancy. In 1949, Davis tried again to make the film, but by that time plans were under way for Katharine Hepburn to star.
- This is the role that won Humphrey Bogart the only Oscar of his career.
- Known as the "LS Livingston", the "Queen of Africa" was a working steam boat for 40 years prior to it being "cast" in the movie.
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