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The working title for the film was Flight to the Future. World Without End was the only feature film credit for Peruvian-born artist Alberto Vargas, famed for painting glamorous images of women for Florenz Ziegfeld's "Ziegfeld Follies" in the 1920s and 1930s. In 1940 Vargas began working for Esquire magazine where he became known for his series of "Varga [later Vargas] Girls," which were replicated in calendars and served as morale boosters throughout WW II.
Several reviews of World Without End commented on the similarities between its plot and that of H. G. Wells's famous novel The Time Machine, which was filmed by M-G-M in 1960. According to a modern source, Wells's estate sued the producers of World Without End for plagiarism, but the outcome of the suit has not been determined.