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The "Tableau Rose (Cornelia's Symphony)" played in the film was written by series co-star Lionel Barrymore, who wrote several classical compositions that were performed by symphony orchestras. This was the last of the Dr. Kildare series to feature Laraine Day in the role of "Nurse Mary Lamont." According to reviews and news items, M-G-M decided to write Day out of the series because her career was advancing and the studio wished to have her free to do other films. A Hollywood Reporter news item in March 1941 noted that Ormond Ruthven, who is credited onscreen as one of four screenwriters, was a member of M-G-M's recorded sound department, and had just sold "an original" to the studio for their next Dr. Kildare picture.
Red Skelton made his second and last appearance in the series as orderly "Vernon Briggs." Skelton also went on to starring roles at M-G-M after leaving the series. Actor Nils Asther, who had been under contract to M-G-M in the 1920s and early 1930s, returned to the studio for the first time in seven years, according to publicity materials. For additional information on the Dr. Kildare series, consult the Series Index and see the entry for Young Dr. Kildare (AFI Catalog of Feature Films, 1931-40; F3.5251).