Cast in the film adaptation of the ABBA stage musical "Mamma Mia!"
Co-starred with John Larroquette in the NBC sitcom "Happy Family"
Played the title role in the Broadway revival of "Mame" at the Kennedy Center
Appeared in a Baltimore production of "She Stoops to Conquer"
Executive produced and starred in the short-lived CBS sitcom "Welcome to New York"
Garnered an Emmy nomination for her memorable guest appearance on NBC's "Frasier" as radio host Dr. Nora
Had featured role as a rauchy biker chick in "The Odd Couple II"
Replaced Judith Ivey on the Broadway stage in the acclaimed production of David Rabe's play, "Hurlyburly"
Replaced Stockard Channing as Bunny Flingus in the acclaimed Broadway revival of John Guare's comedy-drama, "The House of Blue Leaves" (reprised role in the TV version)
Starred in the Encores! presentation of "Promises, Promises" opposite Martin Short at Manhattan's City Center
Starred in the ill-fated musical "Nick and Nora"
Appeared in the comedy "Welcome to Mooseport"
Appeared in the Hollywood/Bollywood satire "The Guru"
Played Dr. Beverly Hofstadter, an unemotional expert in psychiatry and neural science, and Leonard's (Johnny Galecki) mom in "The Big Bang Theory"
Played the wife of Warren Beatty's suicidal US Senator in the political comedy "Bulworth"
Portrayed Andrea Reynolds opposite Irons' Claus von Bulow and Close's Sunny von Bulow in "Reversal of Fortune"
Was a member of the company of the McCarter Theatre in Princeton, New Jersey
Appeared in "Lips Together, Teeth Apart" at the Manhattan Theatre Club
Cast as Mrs. Lovett in the Kennedy Center production of "Sweeney Todd"
Played fading diva opposite Steve Martin and Eddie Murphy in the comedy "Bowfinger"
Starred in the Broadway revival of "Boeing-Boeing"
Played opposite Jessica Chastain in the thriller "Miss Sloane"
Appeared in "A Bad Moms Christmas"
Played opposite Julianna Margulies in the CBS drama "The Good Wife"
Made feature film debut in "Soup for One"
First garnered attention as a meter maid in Louis Malle's comedy "Crackers"
Played reporter Mary Sunshine in the film version of "Chicago"
Co-starred with Glenn Close in Tom Stoppard's Broadway comedy "The Real Thing"; directed by Mike Nichols
Delivered another gemlike comic performance as Kevin Spacey's hoity-toity sister-in-law in "The Ref"
Had supporting role in the landmark CBS TV drama "Playing for Time"
Appeared as Robin Williams' ex-wife in the Mike Nichols-directed "The Birdcage"
Co-starred on Broadway in the Neil Simon comedy "Rumors"; picked up second Tony Award
Had featured role as the title character's childhood sweetheart in "How the Grinch Stole Christmas"
Offered a strong comic turn as a camp counselor in "Addams Family Values"
Returned to the stage as Mrs. Lovett in L.A.'s Reprise! concert production of "Sweeney Todd," co-starring Grammer
Cast as Cybill Shepherd's hard-drinking friend Maryanne Thorpe in the CBS sitcom "Cybill"
Made Broadway debut in "Hide and Seek"
Reprised Diane Lockhart role on "The Good Fight"
Played Tanya in "Mamma Mia! Here We Go Again"