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Like so many of her comedy peers Jamie Denbo was an Upright Citizens Brigade Theatre alumna. She joined the improv and sketch comedy group after moving to New York, often performing with Jessica Chaffin who would become her regular comedy partner. This grounding in live comedy and the reputation of the UCB helped her land her first film role in "Last Night at Eddie's" (1997); She also appeared on TV in the era-defining hit "Sex and the City" (HBO 1998-2004) in 1999 and the "Upright Citizens Brigade" (Comedy Central 1998-2000). She also married fellow UC Brigadier John Ross Bowie, best known for his role as speech-impaired scientist Barry Kripke on "The Big Bang Theory" (CBS 2007-) in 2004. Often popping up on various comedy shows, she became regular on "The Late Late Show with Craig Ferguson" (CBS 2005-) between 2006 and 2008; dabbled with drama appearing in "Cold Case" (CBS 2003-2010) and "Without a Trace" (CBS 2002-09); then went back to the funny stuff as a recurring character in "Reno 911!" (Comedy Central 2003-09) before she scored her first lead on the short-lived sitcom "Happy Hour" (Fox, 2006).
Denbo and Chaffin debuted their most famous characters, a pair of 50-ish Jewish mothers, in the TV movie "Ronna & Beverly" (Showtime 2009), co-written and produced by Denbo. Denbo continued to prove she could also do serious acting with a lead role in cult favorite crime drama "Terriers" (FX 2010) and a recurring role in the critically acclaimed "Weeds" (Showtime 2005-2012). However she never forgot her comedy roots playing a variety of characters on "Childrens Hospital" (Adult Swim 2010-) and "The Life & Times of Tim" (HBO 2008-2010) amongst others. 2011 saw the notorious Ronna & Beverly return hosting a series of podcast interviews with various celebs as well as a live stage show. Their comic personas meant they could ask far cheekier, often inappropriate, questions of their guests. This led to U.K. TV series "Ronna & Beverly" (Sky Atlantic 2012), in which various actors, singers and TV stars were grilled by the overbearing twosome for comic effect. By now Denbo was a regular guest star across the networks cropping up in fellow UCB vet Amy Poehler's sitcom "Parks & Recreation" (NBC 2009-), talk show parody "Comedy Bang! Bang!" (IFC 2012-) and the long-running animated hit "Family Guy" (Fox 1998-). Denbo and Chaffin stole several scenes as a pair of bickering Boston family members in the female-centric buddy cop comedy "The Heat" (2013) alongside Sandra Bullock and Melissa McCarthy.
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