Broadway debut in Michael Weller's "Loose Ends" starring Kevin Kline
Made recurring appearance on NBC's "Saturday Night Live" playing Linda Tripp during the Lewinsky scandal
Performed in children's theater productions and had walk-on or bit parts in off-off-Broadway plays
Played a high-strung FAA agent in the Mike Nichols directed "What Planet Are You From?"
Portrayed a murderously crooked cop in "The Big Easy" opposite Dennis Quaid
Portrayed Bobby Darin's (Kevin Spacey) best friend turned manager, Steve Blauner in "Beyond the Sea"
Portrayed George Herman 'Babe' Ruth in the feature biography "The Babe"
Starred in Roundabout Theatre Company's Broadway production of Samuel Beckett's "Waiting for Godot"
Won an Emmy guest-starring as a judge on Sorkin's NBC drama, "Studio 60 on the Sunset Strip"
Appeared in the NY Shakespeare Festival Central Park staging of "The Seagull" directed by Mike Nichols
Cast in the Los Angeles production of "Antony and Cleopatra"; spotted by casting directors for "Roseanne"
Cast in the touring production of the musical "The Robber Bridegroom"
Cast opposite Steve Carell in "Evan Almighty," a sequel to the 2003 comedy "Bruce Almighty"
Credited as Karl Mundt for his role as the newsreel announcer in the Coen brothers' "The Hudsucker Proxy"
Feature film debut, "Eddie Macon's Run"
Performed in sketches on a NYC monthly radio show called "Citizen Kafka" (WBAI)
Played Pops Racer in the Wachowski brothers' live action film adaptation of the 1960s Japanese series "Speed Racer"
Played Sally Field's insurance-salesman husband in "Punchline"
Portrayed a hyperactive paramedic in Martin Scorsese's "Bringing out the Dead"
Re-teamed with the Coen brothers for "The Big Lebowski"
Re-teamed with the Coen brothers, as a traveling salesman, in "Barton Fink"
Replaced the late John Belushi as Dan Aykroyd's music-making partner in John Landis' sequel "Blues Brothers 2000"
Starred as a college professor on the HBO drama series "Treme"
Breakthrough screen performance as a larcenous lout in the Coen bothers' comic gem "Raising Arizona"
Cast as Mitch in the CBS remake of Tennessee Williams' "A Streetcar Named Desire" opposite Jessica Lange; earned an Emmy nomination for Suporting Actor
First starring role in a feature, "King Ralph"
Left cast of "Big River" to appear in David Byrne's "True Stories"
Played the title character's blue-collar husband on the long running ABC sitcom "Roseanne"; nominated for an Emmy as Lead Actor in a Comedy Series for seven consecutive years (1989-95)
Re-teamed with Quaid for the football-themed "Everybody's All-American"
TV-movie debut, "The Face of Rage" (ABC)
Cast as Bones Darly, an arms dealer opposite Kevin Bacon in the psychological thriller "Death Sentence"
Cast in the short-lived CBS comedy "Center of the Universe"
Co-starred in Randall Miller's "Marilyn Hotchkiss Ballroom Dancing and Charm School"
Co-starred in the Barry Levinson directed HBO film "You Don't Know Jack" about Dr. Jack Kevorkian, played by Al Pacino; earned an Emmy nomination for Outstanding Supporting Actor in a Miniseries or Movie
First stage role in eight years, playing Falstaff in "Henry IV (Parts 1 and 2)" at San Diego's Old Globe Theater
Had a recurring role on Aaron Sorkin's "The West Wing" (NBC) as House Speaker Glen Allen Walken
Moved to New York City to pursue acting
Originated role of Pap Finn (Huck's father) in the American Repertory Theatre production of "Big River"
Played Harry Brock in remake of "Born Yesterday" opposite Melanie Griffith
Played title role (also produced) in the TNT biopic "Kingfish: A Story of Huey P. Long"; earned a Best Actor Emmy nomination
Raised in the St Louis, MO area
Re-teamed with the Coen brothers for the feature "O Brother, Where Art Thou?"
Reprised role of Pap in his Broadway musical debut "Big River"
Returned to the stage, as Harvey 'Big Daddy' Pollitt, the terminally ill, bullying patriarch in Tennessee Williams' "Cat on a Hot Tin Roof"; performed at the Geffen Playhouse
Starred as Fred Flintstone in the live-action feature "The Flintstones"
Nominated for the 2010 Primetime Emmy Award for Outstanding Supporting Actor In A Miniseries Or A Movie ("You Don't Know Jack")
Nominated for the 2011 Screen Actors Guild Award for Outstanding Performance by a Male Actor in a Television Movie or Miniseries ("You Don't Know Jack")
Co-starred with Melissa Leo and Michael Parks in the action thriller "Red State"
Cast in the critically acclaimed black-and-white, nearly silent film "The Artist"
Joined the cast of the crime drama series "Damages" (FX)
Cast in "Extremely Loud and Incredibly Close," Stephen Daldry's feature adaptation of Jonathan Safran Foer's novel; co-starred opposite Tom Hanks and Sandra Bullock
Acted opposite Clint Eastwood in baseball drama "Trouble with the Curve"
Co-starred in political thriller "Argo," directed by Ben Affleck
Cast opposite Denzel Washington in "Flight"