Moved to Laguna Beach, CA and appeared in local production of "John Brown's Body"
Moved over to Universal from Columbia; featured in film "Journey to Shiloh"
Made TV-movie debut, "The Intruders" (NBC)
Earned Best Actor Academy Award nomination as a detective in Peter Weir's "Witness"
Teamed with Weir again for "The Mosquito Coast"
Delivered rare comic turn opposite Melanie Griffith in Mike Nichols' "Working Girl"
Played an adulterous husband with a terrible secret in Alan J. Pakula's "Presumed Innocent"
Played a ruthless litigator transformed by a brain injury in Mike Nichols' "Regarding Henry"
Cast as Dr. Richard Kimble in big screen adaptation of "The Fugitive"
Reprised role of Jack Ryan in "Clear and Present Danger"
Played role originated by Humphrey Bogart in Sydney Pollack's ill-advised remake of "Sabrina"
Starred as a NYC detective opposite Brad Pitt's Irish terrorist in "The Devil's Own"
Played a cargo pilot opposite Anne Heche in romantic comedy "Six Days, Seven Nights"
Starred as widower cop obsessed with learning details of his late wife's affair in Pollack's "Random Hearts"
Played a professor whose wife (Michelle Pfeiffer) is haunted by a ghost in "What Lies Beneath"
Received reported $25 million salary to star as a Russian submarine officer in "K-19: The Widowmaker"
Cast as a security specialist forced into robbing a bank in order to protect his family in thriller "Firewall"
Reprised role of Indy for fourth installment of adventure series "Indiana Jones and the Kingdom of the Crystal Skull"; re-teamed with George Lucas and director Steven Spielberg
Played immigrations officer Max Brogan in "Crossing Over"
Portrayed research scientist Robert Stonehill in "Extraordinary Measures," which ws based on a true story; also produced
Played a morning show anchor in ensemble comedy "Morning Glory"
Co-starred with Daniel Craig in sci-fi Western "Cowboys & Aliens"
Featured in the baseball drama "42"
Appeared in the sci-fi movie "Ender's Game"