Played a jilted wife opposite Peter Falk and John Cassavetes on an episode of "Columbo" (NBC)
Portrayed Nick Nolte's wife in "The Prince of Tides"
Hosted "Sophisticated Ladies: Charleston and Savannah With Blythe Danner" (PBS)
Played Kate Capshaw's mother in "The Love Letter"
Played the mother of Cameron Diaz and Jordana Brewster in "The Invisible Circus"
Reprised her role as Dina Byrnes for the comedy sequel, "Meet the Fockers"
Co-starred with Paul Newman and Joanne Woodward in "Mr. & Mrs. Bridge"
Voiced Martha Jefferson in Ken Burns' PBS documentary "Thomas Jefferson"
Cast as Robert De Niro's understanding wife in the comedy "Meet the Parents"
Cast as Phyllis in the all-star Broadway revival of "Follies"; received a Tony nomination
Co-starred with Richard Chamberlain and Judith Ivey in a revival of Noel Coward's "Blithe Spirit"
Played a woman who comes between two friends in "Lovin' Molly"
Had a supporting role in the NBC production of the Broadway musical "George M!"
Portrayed Martha Jefferson in the movie version of "1776"
Made guest appearance on an episode of "St. Elsewhere" (NBC)
Played featured role in the ABC TV-movie "Dr. Cook's Garden"
Played the co-owner of a NYC restaurant on the short-lived NBC drama, "Tattinger's"; series was retooled as an NBC sitcom called "Nick & Hillary," which lasted only a handful of episodes
Portrayed Arkadina in Williamstown production of "The Seagull" with daughter Gwyneth Paltrow as Nina
Portrayed Elizabeth Custer in "The Court-Martial of General George Armstrong Custer" (ABC)
Portrayed Zelda to Richard Chamberlain's F. Scott Fitzgerald in "F. Scott Fitzgerald and The Last of the Belles'" (ABC)
Made second film with Woody Allen, "Alice"
Spent one season as a member of the Theatre Company of Boston
Was cast in her first Broadway show, the musical "Mata Hari"; show closed during out-of-town tryout
Appeared Off-Broadway in A. R. Gurney's "Sylvia"
Cast as the mother of a child molested by a priest in the HBO drama "Judgment"
Earned critical praise as Eleanor Gehrig in "A Love Affair: The Eleanor and Lou Gehrig Story" (NBC)
Portrayed the matriarch of a troubled family in "The Myth of Fingerprints"
Portrayed the wife of German architect Albert Speer in the ABC miniseries "Inside the Third Reich"
Returned to Broadway appearing alongside Raul Julia and Roy Scheider in Harold Pinter's "Betrayal"; earned a Tony nomination
Starred in the Lincoln Center revival of "The Philadelphia Story"
Appeared in Woody Allen's "Another Woman"
Cast as Dr. Harriet Lanning on the short-lived CBS medical drama "Presidio Med"
Co-starred in "The Last Kiss"; directed by Tony Goldwyn and scripted by Paul Haggis
Co-starred with Edward Herrmann in a staged reading of A. R. Gurney's "Ancestral Voices"
Earned a Tony nomination as Blanche Du Bois in a stage revival of "A Streetcar Named Desire"
Played the wife of a philandering attorney (Anthony Hopkins) who was plotting to kill her in "Guilty Conscience" (CBS)
Re-teamed with daughter Gwyneth Paltrow in the NBC miniseries "Cruel Doubt"
Portrayed Sylvia Plath's mother opposite her real life daughter Gwyneth Paltrow in "Sylvia"
Acted with Trinity Square Repertory Company in Providence, RI
Cast as Amanda on the short-lived ABC sitcom "Adam's Rib"
Starred in the TV-movie "Back When We Were Grownups" (CBS); received Golden Globe and Emmy nominations for Best Actress
Once again reprised the role of Dina Byrnes for the comedy sequel "Little Fockers"
Co-starred with Zac Efron in "The Lucky One," based on the novel by Nicholas Sparks
Cast in romantic comedy "Hello I Must Be Going," starring Melanie Lynskey
Starred in the TV movie "Gilded Lilys"
Co-starred in the dark comedy "Murder of a Cat"
Appeared in romantic comedy "Tumbledown"
Teamed with Frank Langella in the Williamstown production of Tennessee Williams' "Eccentricities of a Nightingale"; production filmed and aired on "Theater in America"
Made NYC debut in the Off-Broadway play "The Infantry"
Played the matriarch of a Jewish family in the film version of Neil Simon's "Brighton Beach Memoirs"
Acted alongside daughter Gwyneth Paltrow in the Williamstown production of "Picnic"
Had breakthrough stage role as the kooky, sexually liberated teenage divorcee Jill Tanner in "Butterflies Are Free"
Garnered attention for her performance in the Lincoln Center productions of "Summertree" (1968) and "The Miser" (1969)
Played the leading lady to Jeff Bridges in "Hearts of the West"
Delivered a strong turn as the devoted wife of a military officer in "The Great Santini"
Played Juliette Lewis' mother in Woody Allen's "Husbands and Wives"
Made professional stage debut as Laura in "The Glass Menagerie"
Starred as Hank Azaria's mother on the Showtime drama "Huff"
Made TV debut on an episode of "N.Y.P.D." (ABC)
Began on-going association with the Williamstown Theatre Festival
Regularly appeared on NBC's "Will & Grace" as Will Truman's mother Marilyn; earned an Emmy nomination for Best Guest Actress in 2005 and 2006
Made feature acting debut in "To Kill a Clown," co-starring Alan Alda
Re-teamed with Alan Alda for a memorable episode of "M*A*S*H*" (CBS)
Cast opposite Anna Faris in the romantic comedy "What's Your Number?"
Co-starred with Sam Elliott and Martin Starr in Brett Haley's drama about life after love, "I'll See You in My Dreams"
Starred as Ruth Madoff on the TV mini-series "Madoff"
Appeared on the Naomi Watts and Billy Crudup-starring Netflix thriller "Gypsy"