Played Joey Buchanan on the ABC soap opera, "One Life to Live"
Co-starred with Keri Russell in the indie, "Waitress"; helmed by Adrienne Shelly, who was murdered before the films release
Appeared in an episode of "The Outer Limits" (Showtime) as a futuristic freedom fighter
Starred as Captain Malcolm Reynolds in the Joss Whedon series "Firefly" (Fox)
Starred as the local sheriff in the horror film, "Slither"
Reprised his role as Captain Reynolds in "Serenity," Whedon's feature-length adaptation of "Firefly"
Acted onstage in Canada's Edmonton Fringe Festival
Made first TV appearance in the TV-movie, "Ordeal in the Arctic" (ABC)
Made his feature film debut in Steven Spielberg's "Saving Private Ryan," playing a soldier with the same name as the sought after James Ryan
Joined the sitcom "Two Guys, a Girl, and a Pizza Place" (ABC) in a supporting role; became a regular cast member in the second season; show was re-titled "Two Guys and a Girl" in the third season and was canceled after the fourth season
Performed in Theatresports, an improvisational acting workshop at Edmonton's Rapidfire Theatre
Was featured as the jealous ex-boyfriend of Alicia Silverstone in "Blast From the Past"
Had a recurring role as Caleb in the final season of Joss Whedon's series "Buffy the Vampire Slayer" (UPN)
Cast in the lead role of Alex Tully in the short-lived series, "Drive" (Fox)
Reprised his role as Joey on two episodes of ABC's "One Life to Live"
Joined the cast of ABC's "Desperate Housewives" as Dr. Adam Mayfair
Appeared in Joss Whedon's Internet-distributed short "Dr. Horrible's Sing-Along Blog" as Captain Hammer
Played the title character of Richard Castle, a mystery novelist who helps the NYPD solve crimes in ABC's "Castle"
Appeared in Whedon's adaptation of "Much Ado About Nothing"
Voiced Johnny Worthington in "Monsters University"
Appeared in the sequel "Percy Jackson: Sea of Monsters"