Professional stage debut in the Canadian production of "Love and Maple Syrup"
Joined the Stratford Shakespeare Festival Company in Ontario, Canada
Spent one season at the Guthrie Theatre in Minneapolis, MN
TV acting debut, the Guthrie staging of "The School for Scandal" (aired on PBS)
NY stage debut in "The Threepenny Opera" at Lincoln Center
Co-starred in the NBC miniseries "Captains and the Kings"
Screen debut, "The Choirboys"
Appeared at the Arena Theater in David Hare's "Plenty"
First starring film role, "Altered States"
Played leading lady to John Belushi in the feature comedy "Continental Divide"
Portrayed Jacqueline Kennedy in the NBC miniseries "Kennedy"
Played the unsuspecting mother of a murderous child in the small screen remake of "The Bad Seed" (ABC)
Starred the series, "The Days and Nights of Molly Dodd" (NBC, 1987-1988; Lifetime, 1989-1991)
Directed by Hare in "Strapless"; role was written expressly for her by Hare
Played the leading role in the Off-Broadway production of "The Secret Rapture"; written by David Hare
Cast as the first woman to lead troops into combat in the Lifetime TV-movie "Majority Rule"
Last feature for six years, "Passed Away"
Debut as TV producer on the NBC movie "Moment of Truth: To Walk Again"; also co-starred
Co-starred in the Broadway production of Tom Stoppard's "Arcadia"
With Toukie Smith, co-hosted the Lifetime talk show "Talk It Over"
Hosted the National Public Radio series "The Poet's Voice"
Played the matriarch of a wealthy family in the CBS miniseries "A Season in Purgatory"
Returned to series TV as co-star of the short-lived CBS drama series "Feds"
Starred as the mother of a murder victim in the based-on-fact Lifetime movie "Convictions"
Succeeded Mary Louise Wilson as Frau Schneider in the acclaimed revival of the stage musical "Cabaret"
Returned to feature films in a supporting role in "The Astronaut's Wife"
Starred opposite Christopher Walken in the NYC stage musical "James Joyce's The Dead"
Won a Tony Award for her performance as the female lead in Michael Frayn's play "Copenhagen"
Played Gertrude in Campbell Scott's TV version of "Hamlet" (Odyssey)
Cast as Desiree in the Kennedy Center production of "A Little Night Music"
Played the lead role in "The Clean House," by playwright Sarah Ruhl
Co-starred with Kyra Sedgwick in the Kevin Bacon directed "Loverboy"; premiered at Sundance (lensed 2003)
Appeared in the murder drama, "Dark Matter" loosely based on the 1991 University of Iowa shootings
Cast as Nina Sharp in the FOX drama "Fringe"