Broadway acting debut as understudy, aged 19, to Rose Hobart in the play, "Tradewinds"; that same year, also understudied Katherine Wilson in the play, "The Vinegar Tree"
Stage breakthrough: played ingenue lead in "Give Me Yesterday"
Took over Margaret Sullavan's role in the hit Broadway play "Dinner at Eight" after Sullavan left the cast
Signed by Universal Studios; first film, "One More River"
Played first female lead in a film, "Great Expectations"
Played one of the female leads in her best-remembered feature film, "Lost Horizon"
Returned to the New York stage to act in "Night Music"
First film in color, "Canadian Pacific" (released in 1949)
Returned to the New York stage to play the role of Nina Denery in "The Autumn Garden"
Last film for six years, "Criminal Lawyer"
Made her TV debut guesting on an installment of the anthology drama series, "Robert Montgomery Presents"
Played Margaret Anderson on the popular family sitcom, "Father Knows Best" (which aired on both CBS and NBC during it initial run)
Only feature film during the run of "Father Knows Best", "Interlude"
First TV-movie, "See How They Run"
Last film for 11 years, "Never Too Late"
Hosted the ABC talk show (with dramatizations included), "Confidential for Women"
Was a panelist on the syndicated TV game show, "Oh My Word"
Fondly remembered career highlight: Playing Amanda, the human mother of the half-Vulcan Mr. Spock on the cult science-fiction TV series, "Star Trek"; guest starred on the episode "Journey to Babel"
Re-entered motion pictures after 11-year absence to act in "Treasure of Matecumbe"
Reprised the role of Margaret Anderson for two TV-movies, "Father Knows Best: The Father Knows Best Reunion" and "Father Knows Best: Home for Christmas"
Played recurring role of Katherine Auschlander on several episodes of the popular NBC medical drama series, "St. Elsewhere" (dates approximate)
Made another one-shot return to features after a decade absence; recreated the role of Amanda for the feature film, "Star Trek IV: The Voyage Home"
Was one of the judges for the "Mother/Daughter USA Pageant"
Suffered mild stroke