Raised on grandmother's farm in Mississippi
Moved to Milwaukee to live with her mother at age six
Went to live with father in Nashville, TN where she became an honor student and joined drama club
Crowned Miss Fire Prevention in Nashville at age 17
Won Miss Black Tennesee pageant
Competed in Miss Black America pageant
Started as radio reporter while still a Nashville high school student
At age 19, became the first black anchor on Nashville's WVOL nightly newscast; later moved to the CBS affiliate WTFV-TV (1975)
Moved to Baltimore; worked as TV feature reporter and co-anchor for WJZ-TV
Co-hosted morning talk show "People Are Talking"
Moved to Chicago; hosted own half-hour TV show "AM Chicago"
"AM Chicago" expanded to one hour and renamed "The Oprah Winfrey Show"
Breakthrough acting debut, "The Color Purple"; earned Best Supporting Actress Oscar nomination
"The Oprah Winfrey Show" picked up for national syndication; premiered in syndication on September 8
Hosted first TV special "A Star-Spangled Celebration"
Landed second film role as Mrs. Thomas, the mother of an accused murderer in "Native Son"
Assumed ownership and production of "The Oprah Winfrey Show" through Harpo Productions
Executive produced and acted in the TV movie "Women of Brewster Place" (ABC)
Executive produced and acted on the short-lived ABC spin-off series "Brewster Place"
Executive produced "Michael Jackson Talks...To Oprah ¿ 90 Primetime Minutes With the King of Pop" (ABC)
Portrayed LaJoe Rivers in "There Are No Children Here" (ABC)
Finished a marathon (26.2 miles) alongside trainer Bob Greene
Renewed contract with King World to continue hosting talk show through 1997; signed deal with Capital Cities/ABC Inc to provide primetime programming beginning in the 1996-97 TV season; signed multi-picture deal with Walt Disney Company and announced first feature would be an adaptation of Toni Morrison's "Beloved"
Began regular segment "Oprah's Book Club"
Appeared as a therapist on the celebrated "coming out" episode of "Ellen" (ABC)
Renewed contract with King World to continue talk show through the year 2000
Stayed in Amarillo, TX for six weeks, defending herself in $10 million libel suit brought by a group of cattlemen over some offhand remarks uttered on her talk show; she won in a victory for the First Amendment
Executive produced the ABC miniseries "The Wedding," adapted from the novel by Dorothy West
At start of 13th season on TV, introduced "change your life television" featuring numerous guests culled from the ranks of self-help authors; also debuted a new theme to show "Run On," which she sang lead vocals; also began Oprah's Angel Network
Signed contract to host TV talk show through the 2001-02 season
Served as executive producer of the ABC remake of "David and Lisa"
Starred in and produced an adaptation of Toni Morrison's novel "Beloved"
In November, joined with Geraldine Laybourne (of Oxygen Media) and Marcy Carsey (of Carsey-Werner-Mandabach) in announcing plans to create Oxygen, a new cable channel aimed specifically at women
In July, announced joint venture with Hearst Magazines to publish new magazine aimed at women and covering spiritual issues
Executive produced the highly-rated TV-movie "Oprah Winfrey Presents: Tuesdays With Morrie" (ABC); won Emmy as Outstanding Made for Television Movie
Began honoring everyday heroes on her talk show via the "Use Your Life" award
Launched the magazine <i>O, The Oprah Magazine</i> (April)
Executive produced another popular TV movie "Amy & Isabelle" (ABC)
In March, signed deal to remain with "The Oprah Winfrey Show" through the 2005-06 season
Made <i>Forbes</i> magazine's Billionaire's list, the first black woman to do so and only the second African-American billionaire (after BET founder Robert Johnson) with a reported net worth of $1 billion
Produced and invested more than $1 million in the Broadway musical adaptation "Oprah Winfrey Presents: The Color Purple"; the show earned 11 Tony nominations
Signed a three-year, $55 million deal to debut a new XM Satellite Radio channel titled "Oprah & Friends"; channel aired programming related to fitness, health, and self-improvement
Signed on with Simon & Schuster to pen a book about weight control, reportedly receiving more than $12 million
Voiced Gussy the goose in live-action/computer-animated feature film "Charlotte's Web"
Invested $40 million and much of her time establishing the Oprah Winfrey Leadership Academy for Girls near Johannesburg in South Africa (opened in January)
Oprah Winfrey and Discovery Communications announced plans to create OWN: The Oprah Winfrey Network
Voiced Judge Bumbleden in "Bee Movie," co-starring the voices of Jerry Seinfeld and Renee Zellweger
Teamed with Tyler Perry to produce the drama "Precious," a movie based on the novel <i>Push</i> by Sapphire
Announced plans to end highly rated "The Oprah Winfrey Show" in 2011 after 25 years
Voiced the title character's mother Eudora in Disney animated feature "The Princess and the Frog"
Launched OWN: The Oprah Winfrey Network; programming included "Oprah's Next Chapter" and "Oprah Presents: Master Class"
Received the Jean Hersholt Humanitarian Award from the Academy of Motion Picture Arts and Sciences
Co-starred in the historical drama "Lee Daniels' The Butler"
Small role as Annie Lee Cooper in "Selma"