Suffered a series of potentially crippling diseases during childhood, including polio, rheumatic fever and hepatitis
Became Canada's (Nova Scotia) youngest radio announcer and disc jockey at age 14
Played Scrooge in a radio production of Dickens' "A Christmas Carol"
Made stage debut in "The Male Animal" at the Hart House Theatre in Toronto
Moved to England to study at the London Academy of Music and Dramatic Art
Began acting in British TV and repertory theater
Acted with the Perth Repertory Theatre in Scotland
London stage debut, "August for the People"
First significant film role, "Il Castello dei Morti Vivi/Castle of the Living Dead"
Made U.S. TV debut on the ABC series "Court Martial"
Breakthrough supporting role, "The Dirty Dozen" with Lee Marvin and Charles Bronson
Received strong notices as a flamboyant wealthy young man in "Joanna"
Soared to stardom as the original Hawkeye Pierce in Robert Altman's "M*A*S*H"
Portrayed a prototypical hippie in the WWII comedy-drama "Kelly's Heroes"
Reteamed with Elliott Gould (from "M*A*S*H") for Alan Arkin's "Little Murders"
Played Jesus Christ in Dalton Trumbo's "Johnny Got His Gun"
Delivered an outstanding performance as detective opposite then-girlfriend Jane Fonda in "Klute"
Feature debut as co-producer and co-writer for the anti-Vietnam war film "F.T.A."; featured a series of anti-war skits and songs (with Fonda) performed outside army bases
Starred opposite Julie Christie in Nicolas Roeg's "Don't Look Now"
Executive produced "Steelyard Blues" (also starred with Fonda)
Re-teamed with Gould in "S.P.Y.S."
Evoked pity as the hick in love with an aspiring, selfish would-be starlet (Karen Black) in John Schlesinger's "The Day of the Locust"
Played a bestial fascist in Bernardo Bertolucci's "1990"
Delivered a romantic turn as the title role of "Fellini's Casanova"
Delivered arguably his best performance since "Klute" as scientific-minded public health inspector confronting unspeakable horrors in Phillip Kaufman's remake of "Invasion of the Body Snatchers"
Teamed with Sean Connery for the stylish "The Great Train Robbery"
Came to see the falseness of his life as he struggled to overcome the death of his son in the Academy Award-winning "Ordinary People", co-starring Mary Tyler Moore and Timothy Hutton; film marked Robert Redford's directorial debut
Broadway debut as Humbert Humbert in Edward Albee's stage adaptation of "Lolita"
Founded McNichol Pictures Inc.; also served as President
Played a German agent in the thriller "Eye of the Needle"
Appeared in "Max Dugan Returns" along with son Kiefer in his film debut (also debut of Matthew Broderick)
Returned to TV after a 15-year absence in the CBS movie "John Steinbeck's 'The Winter of Our Discontent'"
Portrayed middle-aged Paul Gauguin in "Wolf at the Door"; also provided voice of Gauguin in PBS' "Paul Gauguin: The Savage Dream" (1989)
Cast as a teacher in the South African apartheid drama "A Dry White Season"
Cast as a mad firebug in Ron Howard's "Backdraft"
Played a mysterious Washington intelligence officer in Oliver Stone's "JFK"
Mentored Kristy Swanson in the feature "Buffy the Vampire Slayer"
Offered a captivating performance as a snobbish but charming, upscale New Yorker living through the eyes of other people in "Six Degrees of Separation"; film based on a 1990 play by John Guare
Portrayed a corporate honcho in Barry Levinson's adaptation of Michael Crichton's "Disclosure"
Narrator for The Learning Channel's "Great Books" series
Offered an award winning performance as Colonel Fetisov in the HBO movie "Citizen X"
Came aboard "Outbreak" late to play the icy General McClintock
Second film with son Kiefer, as the alcoholic mentor of Jake Brigance (Matthew McConaughey) in "A Time to Kill"
Cast as a coldly manipulative CIA agent in "The Assignment"
Stalked the hidden enemy in the supernatural thriller "Fallen"
Played University of Oregon track coach Bill Bowerman in Robert Towne's "Without Limits," about track sensation Steve Prefontaine
Acted on stage in "Enigma Variations"
Starred as a painter in the off-Broadway play "Ten Unknowns" by Jon Robin Baitz
Had lead role as an Irish thief who plans to rob an airport terminal in the A&E original "The Big Heist"
Had memorable role in F. Gary Gray's remake of the "Italian Job"
Cast in Anthony Minghella's war epic "Cold Mountain"
Cast as Speaker of the House Nathan Templeton on Rod Lurie's ABC drama "Commander in Chief"; earned a Golden Globe nomination for Best Supporting Actor
Cast as the patriarch in Joe Wright's adaptation of the Jane Austen classic "Pride and Prejudice"
Co-starred with Mira Sorvino in the Lifetime movie "Human Trafficking"; earned Golden Globe and Emmy nominations for Best Actor in a TV movie
Co-starred with Colin Farrell in the Robert Towne-directed adaptation of "Ask the Dust"
Played a Virginia firearms-shop owner in Aric Avelino's film debut "American Gun"
Played an aging aristocratic billionaire in Griffin Dunne's "Fierce People"
Cast as Patrick 'Tripp' Darling III on ABC's "Dirty Sexy Money"; earned a Golden Globe (2008) nomination for Best Supporting Actor in a Series
Played multi-millionaire Nigel Honeycut in "Fool's Gold"
Lent his voice to the animated feature "Astro Boy"
Received a star on the Hollywood Walk of Fame
Cast as series antagonist President Snow in the feature film adaptation of "The Hunger Games"