While a pre-med student at Yale College, played a lead in the European production of Leonard Bernstein's "Mass" at age 19
Urged by Bernstein to study acting in New York
Bernstein informed Picardo's mother that her son was switching his major from biology to drama
Moved to NYC at age 20; enrolled at the Circle in the Square Professional Theater Workshop
Professional acting debut, off-Broadway production of David Mamet's "Sexual Perversity in Chicago"
Acted on stage with Diane Keaton in "The Primary English Class"
Broadway debut, a lead in "Gemini" with Danny Aiello
Played opposite Jack Lemmon in the Broadway production of "Tribute"
Reprised his role in the L.A. production of "Tribute" caught the attention of director Joe Dante
Feature acting debut, "The Howling"; first of numerous collaborations with director Joe Dante
TV miniseries debut, "The Dream Merchants" (syndicated)
Debut as a TV series regular, "Steambath", a Showtime fantasy based on the off-Broadway play set in a steambath in the hereafter
First appearance in a TV special "Michael Nesmith in Television Parts"
First TV collaboration with Dante, "Boo", an episode of the Steven Spielberg-produced fantasy anthology series "Amazing Stories"
Played Dr. Dick Richard, a regular character on the war drama series "China Beach"
Played the recurring role of Coach Cutlip on "The Wonder Years", the popular sitcom set in the late 1960s; received 1989 Emmy nomination as Guest Actor in a Comedy Series
Provided the voice for the Johnnycab that takes Arnold Schwarzenegger for a ride in "Total Recall"
Provided various voices for "Dinosaurs", a children's puppet show from Jim Henson Productions
Played a recurring role on the hit sitcom "Home Improvement" (ABC)
First TV-movie collaboration with Dante, "Runaway Daughters", an installment of Showtime's "Rebel Highway" series
Portrayed the initially unnamed holographic doctor on the hit spin-off "Star Trek: Voyager" (UPN); also directed two episodes and scripted one
Hosted the syndicated TV special "Inside the New Adventure--Star Trek: Voyager"