Played Cleopatra at the Old Vic with the National Youth Theater at age 18
Joined Royal Shakespeare Company
Made TV debut in BBC production of "Herostradus"
Played Hermia in a British TV adaptation of "A Midsummer's Night Dream"; directed by Peter Hall (released theatrically in the USA)
Had supporting role in the BBC production of "Cousin Bette"; aired on PBS' "Masterpiece Theater" in 1972
Toured Africa and America with Peter Brook's theater company
Co-starred in Ken Russell's "Savage Messiah" and had title role in film "Miss Julie"
Starred opposite Michael Jayston in the thriller "Kiss Kiss, Kill Kill" (ABC); film aired in Great Britain as "Coffin for the Bride"
Garnered acclaim for her stage performance in "The Sea Gull"
Starred opposite Laurence Olivier, Alan Bates and Malcolm McDowell in British TV adaptation of Harold Pinter's play "The Collection"
Had lead role of Rosalind in the BBC/PBS production of Shakespeare's "As You Like It"; part of a series in which all the Bard's plays were performed
Was featured as Morgana (aka Morgan Le Fey) in John Boorman's "Excalibur"
Cast as the fairy queen Titania in the BBC/PBS adaptation of "A Midsummer Night's Dream"
Played Imogen in the BBC/PBS version of Shakespeare's "Cymbeline"
Had second go as the Egyptian queen in "Antony and Cleopatra" opposite Michael Gambon
Cast as a Russian astronaut in "2010"
Met future husband Taylor Hackford when he directed her in "White Nights"
Acted opposite Ben Kingsley in "Pascali's Island"
Co-starred with Rupert Everett in the thriller "The Comfort of Strangers"
Played the queen in "Prince of Jutland/Royal Deceit," a drama that purported to tell the "real" story of Hamlet
Made Broadway debut in "A Month in the Country"; received a Tony nomination
First screen credit as associate producer on "Some Mother's Son"; also starred as an Irishwoman whose son is imprisoned for alleged IRA activities
Associate produced and starred as a faded rock singer turned sleuth in the British TV mystery "Painted Lady"; aired on PBS in the USA
Starred opposite Alan Rickman in the London stage production of "Antony and Cleopatra"
Voiced the Queen in the animated feature "The Prince of Egypt"
Portrayed the title role in the Showtime film "The Passion of Ayn Rand"
Cast as the titular educator in the black comedy "Teaching Mrs. Tingle"
Returned to the London stage in "Collected Stories"
Co-starred opposite Stuart Townsend in the Donmar staging of "Orpheus Descending"
Directed the short "Happy Birthday" (filmed 2000); aired on Showtime as part of <i>Directed By</i> series in the edition entitled "On the Edge"
Returned to Broadway opposite Ian McKellen in "The Dance of Death"
Cast as a ruthless TV news producer in Hal Hartley's "No Such Thing"
Co-starred in the television movie "Door To Door"
Starred in the television feature "The Roman Spring of Mrs. Stone"
Returned as Inspector Jane Tennison to the PBS Masterpiece Theatre miniseries "Prime Suspect 6: The Last Witness''; received an Emmy nomination for Outstanding Actress in a Miniseries or Movie (2004)
Appeared in the Comedy "Raising Helen" directed by Garry Marshall
Co-starred with Robert Redford and Willem Dafoe in the thriller "The Clearing"
Starred opposite Cuba Gooding Jr. in Lee Daniels' indie film "Shadowboxer"
Reprised role of Inspector Jane Tennison in the PBS Masterpiece Theatre miniseries "Prime Suspect: The Final Act"; received a Golden Globe nomination for Best Actress in a Miniseries or Television Movie
Offered an award winning performance as the Queen of England in the Channel 4/HBO joint production of "Elizabeth I"
Published her memoir, <i>In the Frame</i>
Cast as the ruthless editor of the <i>Washington Globe</i> in the political thriller "State of Play"
Starred in "Love Ranch," based on the true story of a married couple who opened the first legal brothel in Nevada; her husband Taylor Hackford directed the film
Co-starred with Bruce Willis in "Red," an adaption of the comic book mini-series of the same name
Starred as Prospera in the Julie Taymor-directed adaptation of Shakespeare's "The Tempest"
Played Hobson, the title character's nanny in the remake of "Arthur," opposite Russell Brand
Played a former Mossad agent in "The Debt"
Portrayed the filmmaker's wife and longtime creative partner Alma Reville in "Hitchcock"
Featured in Pixar's "Monsters University"
Starred in the action sequel "Red 2"
Starred in culinary romance "The Hundred-Foot Journey"
Starred opposite Ryan Reynolds in "Woman In Gold," a drama about Nazi-looted art following World War II
Co-starred with Aaron Paul and Alan Rickman in war thriller "Eye in the Sky"
Portrayed Hollywood gossip columnist Hedda Hopper in Hollywood Blacklist biopic "Trumbo"