Made her film debut playing the girlfriend of troubled teenager, Conrad (Timothy Hutton) in "Ordinary People"
Made stage debut in "To Be Young, Gifted and Black"
Earned an Academy Award nomination for her role as Evelyn Nesbit in the film, "Ragtime"
Starred as Robert De Niro's romantic interest in Sergio Leone's gangster epic, "Once Upon a Time in America"
Co-starred with Sean Penn and Nicolas Cage in "Racing with the Moon"
Starred in the Curtis Hanson thriller, "The Bedroom Window"
Played Kevin Bacon's wife in John Hughes' "She's Having a Baby"
Played Mickey Rourke's girlfriend in "Johnny Handsome"
Made her TV debut in "The Man in the Brooks Brothers Suit," a segment of HBO's "Women & Men: Stories of Seduction"
Directed by husband, Simon Curtis in the BBC production of "The Changeling"
Cast as regular in the short-lived CBS sitcom, "If Not for You"
Had featured role in "The Wings of the Dove"
Played Marguerite St. Just in the BBC/A&E adaptation of "The Scarlet Pimpernel"
Appeared in the London stage production of "Three Days of Rain," alongside Colin Firth and David Morrissey
Had featured role in the big screen adaptation of "The House of Mirth"
Acted in the London stage production of "Dinner With Friends"
Performed in "The Vagina Monologues" in London
Co-starred in the feature "Buffalo Soldiers"
Had a featured role in the short-lived CBS series, "The Brotherhood of Poland, New Hampshire"
Starred in the ABC Family channel's "Three Moons Over Milford"
Featured in the BBC2 television drama "Daphne"
Appeared in the three-part BBC comedy series "Freezing"; written by James Wood and directed and co-produced by her husband, Simon Curtis
Had a small role in the superhero comedy "Kick-Ass"
Played the leading role of Cora, Countess of Grantham on the British TV series "Downton Abbey" (PBS)
Nominated for the 2011 Primetime Emmy Award for Outstanding Lead Actress In A Miniseries Or A Movie
Co-starred with Felicity Jones in "Cheerful Weather for the Wedding"